Lactation At the least a person Loss of life was described within a nursing toddler who was subjected to high levels of morphine in breast milk as the mother was an ultra-quick metabolizer of codeine.
This medicine may possibly cause you to dizzy, drowsy, bewildered, or disoriented. Usually do not travel or do anything which could be risky until you know how this medication influences you.
Ideal studies have not been carried out on the connection of age to the consequences of codeine during the pediatric population. It should not be Utilized in youngsters young than 12 many years of age. Safety and efficacy have not been recognized.
Promethazine can interfere with the outcomes of dwelling pregnancy checks. Speak with your health practitioner if you're thinking that there's a chance you're pregnant if you are getting promethazine. Never test to test for pregnancy at home.
If another person has overdosed and has really serious signs or symptoms for example passing out or issues breathing, contact 911. Normally, get in touch with a poison control Heart straight away.
Check your neighborhood drug retail store and clinics for choose-back again destinations. You can also Test the DEA Website for locations. Here's the link towards the FDA safe disposal of medicines Internet site:
Due to the fact these reactions may be described voluntarily from the population of uncertain dimension, It isn't often attainable to reliably estimate their frequency or establish a causal partnership to drug publicity.
The concomitant utilization of Promethazine with Codeine Oral Answer with all cytochrome P450 3A4 inducers or discontinuation of the cytochrome P450 3A4 inhibitor may possibly cause lower codeine levels, higher norcodeine degrees, and less metabolism by means of 2D6 with resultant reduced morphine concentrations. This can be affiliated with a lessen in efficacy, and in some patients, could lead to indications and indications of opioid withdrawal.
When employed for an prolonged time, this medication may not get the job done too and will demand various dosing. Talk with your medical professional if this medication stops Performing properly.
Promethazine with Codeine Oral Answer has codeine, a Routine V controlled material. Being an opioid, Promethazine with Codeine Oral Answer exposes people for the dangers of habit, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (nine)], which may lead to overdose and Loss of life [seeOVERDOSAGE (ten)]. Reserve Promethazine with Codeine Oral Alternative for use in adult sufferers for whom the advantages of cough suppression are predicted to outweigh the threats, and in whom an satisfactory assessment in the etiology in the cough has actually been manufactured. Evaluate Each individual individual's hazard prior to prescribing Promethazine Promethazine codeine syrup with Codeine Oral Solution, prescribe Promethazine with Codeine Oral Solution with the shortest length that may be in line with particular person affected individual treatment targets, keep track of all patients on a regular basis for the event of dependancy or abuse, and refill only right after reevaluation of the need for ongoing therapy.
Acute or critical bronchial bronchial asthma in an unmonitored setting or in absence of resuscitative gear. (four)
Stomach or bowel blockage (like paralytic ileus)—Should not be Employed in sufferers with these disorders.
Should you be taking promethazine liquid, usually do not utilize a domestic spoon to measure your dose. Make use of the measuring spoon or cup that arrived With all the medication or utilize a spoon produced specifically for measuring medication.
The following really serious adverse reactions are described, or explained in better element, in other sections: